Selank: what one human trial and twenty lab reports found.

What kind of medicine is Selank?

Poor sleep can follow a day of worry. Lab workers make Selank. The medicine has 7 small protein parts. Their letter names don't help with a health choice.

Russian lab teams built Selank with a substance called tuftsin. The body cuts tuftsin from a larger immune protein. Three more protein parts slow Selank's breakdown. Russia approved a prescription nose spray in 2009.

Animal and cell work offers three possible reasons. Selank may change how the brain calms itself. It may keep the body's own pain-soothing chemicals around longer. It may also raise a protein used for brain-cell upkeep.

One Russian trial and animal work found few harms. That doesn't settle safety over months or years. The FDA and the European medicine agency haven't cleared Selank. The research page, study amounts page, and questions page give the details. Those pages can't predict how your body would respond.

What did the main Selank studies find?

Russian groups have studied Selank for about thirty years. In animals, it eased fearful acts without clear drug tolerance. Researchers offered at least seven possible reasons. They concern calm, pain relief, brain-cell care, mood, stress, drive, and immune defenses ^{[1][3][4][12][14]}.

The only human treatment trial included 62 people. They had anxiety or lasting fatigue. Selank went into the nose at 2,700 micrograms per day for 14 days. That amount is measured in millionths of a gram. Three rating forms found similar anxiety relief with medazepam, an older anxiety pill. Selank also helped fatigue and alertness in ways that pill didn't ^[5].

Another study put 52 healthy adults in a brain scanner. Within 20 minutes, two brain areas worked together differently. Those areas help with fear and memory ^[20]. A changed scan doesn't promise that an illness will improve.

Most of this work came from Russia. Independent teams abroad seldom repeated it. The human claim rests on one 62-patient trial. Safety over years is still unknown. The Selank and Semax page compares them. The withdrawal page covers tolerance and dependence.

What parts make up Selank?

Name and parts. Selank has 7 small protein parts. It copies tuftsin, which the body cuts from a larger immune protein. Added parts help it last longer.

Time in blood. The whole Selank chain stays in blood about 3–5 minutes. Some animal effects lasted past that short time. Smaller pieces may still work after the chain breaks. See what that blood time means.

How it was studied. Human studies gave Selank through the nose. Animal studies also used belly shots and shots under the skin. Russia approved a nose spray in 2009. The FDA and the European medicine agency haven't cleared it. None of these routes sets a plan for your care.

N-Acetyl Selank Amidate is a separate version of Selank. Its name refers to one small change at each end. Those changes may slow the body's cutting process. Fair side-by-side studies are scarce. The Selank forms page gives the known facts.

Which Selank page answers each question?

Each page answers one question for you. These links keep the human facts apart from lab clues. You can return to the exact study later.

• /research says what changed in people, animals, and cells. It covers calm, stress, learning, immune changes, and the human trial.
• /dosage lists the amounts and timing used in studies. It keeps nose doses separate from belly and skin shots.
• /vs-semax compares Selank with Semax. It explains how their brain scans and main study aims differed.
• /withdrawal covers tolerance and withdrawal. It also reports the morphine and alcohol tests in rats.
• /faq answers thirty common questions. Each answer names the kind of study behind it.
• /references gives each paper's full title and web link. The numbered notes on other pages lead back there.